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ID number:862778
 
Author:
Evaluation:
Published: 14.10.2014.
Language: Latvian
Level: College/University
Literature: 3 units
References: Not used
Extract

Diferenciāldiagnostika
WG
var būt perifēra eozinofīlija (citām slimībām neraksturīgi)
MPA
Poliarterītis nodosa
Mikroaneirismas, bet PA nav raksturīgi astma un GN
Eo infiltratīvās slimības
Lofēra sindroms
Hroniska eozinofīla pneimonija – nav ekstrapulmonālu izpausmju
Hiper eozinofilais sindroms
Nav vaskulīta
Eo > 100 000 š/mm3

Ārstēšana
GK monoterapija
Prednizolons 1mg/kg/dienā vai 40-60mg 6-12ned
GK + citostatiķi
KS pulsterapija
Cikofosfamīds pulsterapija 500-1000mg/m2 1-2x mēnesī 3 mēnešus
Rituximabs rezistenta ČSS gadījumā.

Prognoze
1 gada dzīvildze 90%
5 gadu dzīvildze 78.9% (62%)
Prognozi pasliktina
Kreatinīns >1.58mg/dL / 140mkmol/l
Proteinūrija > 1g/d
GI trakta iesaiste
Kardiomiopātija
CNS iesaiste

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