Parathormone (PTH) is a polypeptide of 84 amino acids that is produced and secreted by parathyroid chief cells. PTH regulates the concentration of calcium ions (Ca2+) in the blood, this is important because Ca2+ is need for proper muscle and nerve function. Low calcium blood levels (hypocalcemia) cause muscle spasms, tetany and cardiac problems. PTH also regulates blood phosphate and magnesium levels. High blood calcium levels (hypercalcemia) with high blood phosphate levels can cause precipitation of calcium phosphate leading to organ damage.
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