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ID number:336966
Author:
Evaluation:
Published: 23.11.2018.
Language: Latvian
Level: College/University
Literature: 5 units
References: Not used
Extract

Secinājumi
Dioksidaza zaļu formas biopieejamības pētijumā uz žurkām (liofilizēts pulveris, kas satur vienā ampulā 100 mg dioksidīna un 250 mg izoniazīda), konstatēts:
Kombinētā lietošanā izoniazīds neietekmē dioksidīna biopieejamību. Dioksidina koncentrācijas (pētīta laika intervālā) ir gandrīz vienādas.
Pie kombinētas lietošanas samazinās izoniazīda koncentrācija asinīs un palielinās aknās, salīdzinot ar individuālo intraperitoneālo preparata ievadīšanu ekvimolārās devās.

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